Skip Navigation


The Journals of Gerontology Series B: Psychological Sciences and Social Sciences Advance Access originally published online on July 17, 2009
The Journals of Gerontology Series B: Psychological Sciences and Social Sciences 2009 64B(5):577-585; doi:10.1093/geronb/gbp061
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow All Versions of this Article:
64B/5/577    most recent
gbp061v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Wolinsky, F. D.
Right arrow Articles by Tennstedt, S. L.
PubMed
Right arrow PubMed Citation
Right arrow Articles by Wolinsky, F. D.
Right arrow Articles by Tennstedt, S. L.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© The Author 2009. Published by Oxford University Press on behalf of The Gerontological Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oxfordjournals.org.

The ACTIVE Cognitive Training Interventions and the Onset of and Recovery from Suspected Clinical Depression

Fredric D. Wolinsky1,2, Henry W. Mahncke3, Mark W. Vander Weg1,4, Rene Martin1,5, Frederick W. Unverzagt6, Karlene K. Ball7, Richard N. Jones8 and Sharon L. Tennstedt9

1 Center for Research in the Implementation of Innovative Strategies into Practice, Iowa City VAMC, Iowa
2 Department of Health Management and Policy, University of Iowa, Iowa City
3 Department of Research and Outcomes, Posit Science Corporation, San Francisco, California
4 Department of Internal Medicine, University of Iowa, Iowa City
5 College of Nursing, University of Iowa, Iowa City
6 Department of Psychiatry, Indiana University School of Medicine, Indianapolis
7 Department of Psychology, University of Alabama at Birmingham
8 Institute for Aging Research, Hebrew Senior-Life, Boston, Massachusetts
9 Department of Behavioral and Social Science Research, New England Research Institutes, Boston, Massachusetts

Address correspondence to Fredric D. Wolinsky, PhD, Department of Health Management and Policy, University of Iowa, 200 Hawkins, GH E205, Iowa City, IA 52242. Email: fredric-wolinsky{at}uiowa.edu


  Abstract

We evaluated the effects of the 3 cognitive interventions fielded in the Advanced Cognitive Training for Independent and Vital Elderly study on 2 subsets of participants—1,606 without and 424 with suspected clinical depression at baseline. In the former group, only the speed of processing (vs. no-contact control) intervention had a significant effect, with its participants being 38% less likely to develop suspected clinical depression at 1 year (adjusted odds ratio = 0.62; p < .01). None of the interventions had a significant effect on recovery from suspected clinical depression in the latter group. Although the etiological mechanism of the speed of processing’s protective effect was not isolated, it may result from successful adaptation to age-related changes through selective optimization with compensation.

Key Words: ACTIVE • Depression • Randomized controlled trial • Speed of processing

Received June 18, 2008; Accepted May 27, 2009

Decision Editor: Elizabeth Stine-Morrow, PhD


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?




Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.