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The Journals of Gerontology Series B: Psychological Sciences and Social Sciences Advance Access originally published online on October 5, 2009
The Journals of Gerontology Series B: Psychological Sciences and Social Sciences 2009 64B(6):687-695; doi:10.1093/geronb/gbp071
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© The Author 2009. Published by Oxford University Press on behalf of The Gerontological Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oxfordjournals.org.

Comparison of Patient and Caregiver Reports of Patient Activity Participation and Its Relationship to Mental Health in Patients With Alzheimer's Disease

Karen L. Siedlecki1, Oksana Tatarina1, Linda Sanders1, Marilyn Albert2, Deborah Blacker3, Bruno Dubois4, Jason Brandt5 and Yaakov Stern1

1 Cognitive Neuroscience Division, Taub Institute, Columbia University, New York
2 Department of Neurology, Johns Hopkins University, Baltimore, Maryland
3 Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts
4 Department of Neurology, Hôpital de la Salpêtrière, Paris, France
5 Psychiatry and Behavioral Sciences, Johns Hopkins University, Baltimore, Maryland

Address correspondence to Karen L. Siedlecki, PhD, Cognitive Neuroscience Division, Taub Institute, Columbia University, 630 West 168th Street, New York, NY 10032, USA. Email: ks2513{at}columbia.edu.


   Abstract

The relationship between engagement in pleasant activities as rated by the patient and as rated by the caregiver from the patient's perspective was examined using structural equation modeling in a sample of patients (N = 277) diagnosed with mild to moderate Alzheimer's disease. The two activity participation ratings were only moderately related to one another. Furthermore, depression was the only significant predictor of the patient-rated activity participation, whereas severity of depression, degree of personality change, level of dependence, and cognition were all significant predictors of caregiver-rated activity participation. These findings suggest that caregivers consider a wider range of variables when evaluating the patient's engagement in activities than does the patient. Predictors of patient-rated activity participation did not differ as a function of age or cognition.

Key Words: Activities • Alzheimer's disease • Invariance analyses • Structural equation modeling

Received October 6, 2008; Accepted July 27, 2009


Decision Editor: Rosemary Blieszner, PhD


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